Pharmacodynamics ceftiofur ndi gulu la β-lactam la mankhwala ophera mabakiteriya, okhala ndi bactericidal yotakata, yogwira ntchito motsutsana ndi mabakiteriya a gram-positive ndi gram-negative (kuphatikiza mabakiteriya otulutsa β-lactamase). Limagwirira ake antibacterial ndi ziletsa synthesis wa bakiteriya selo khoma ndi kuchititsa imfa ya mabakiteriya. The tcheru mabakiteriya makamaka pasteurella multiplex, pasteurella hemolyticus, actinobacillus pleuropneumoniae, salmonella, escherichia coli, streptococcus, staphylococcus, etc. Ena pseudomonas aeruginosa, enterococcus kugonjetsedwa. Antibacterial ntchito ya mankhwalawa ndi yamphamvu kuposa ya ampicillin, ndipo ntchito yolimbana ndi streptococcus ndi yamphamvu kuposa fluoroquinolones.
Pharmacokinetics ceftiofur imatengedwa mwachangu komanso mochuluka ndi jakisoni wa intramuscular ndi subcutaneous, koma sangadutse chotchinga chamagazi muubongo. The ndende ya mankhwala ndi mkulu magazi ndi zimakhala, ndi ogwira magazi ndende anakhalabe kwa nthawi yaitali. The yogwira metabolite desfuroylceftiofur akhoza kupangidwa mu thupi, ndi zina zimapukusidwa mu ofooka mankhwala excreted mu mkodzo ndi ndowe.
β-lactam mankhwala. Amagwiritsidwa ntchito pochiza matenda a bakiteriya a ziweto ndi nkhuku. Monga nkhumba bakiteriya kupuma thirakiti matenda ndi nkhuku escherichia coli, salmonella matenda.
Ceftofur amagwiritsidwa ntchito. Mu mnofu jekeseni: Mlingo umodzi, 1.1- 2.2mg pa 1kg thupi ng'ombe, 3-5mg nkhosa ndi nkhumba, 5mg nkhuku ndi bakha, kamodzi pa tsiku kwa 3 masiku.
Jakisoni wa subcutaneous: anapiye a tsiku limodzi, 0.1mg pa nthenga.
(1) Zingayambitse kusokonezeka kwa zomera za m'mimba kapena matenda awiri.
(2) Pali vuto linalake la kukomoka.
(3) Kupweteka kosakhalitsa komweko kungachitike.
(1) Gwiritsani ntchito pano.
(2) Mlingo uyenera kusinthidwa kwa nyama zomwe zili ndi vuto la aimpso.
(3)Anthu omwe amakhudzidwa kwambiri ndi maantibayotiki a beta-lactam ayenera kupewa kukhudzana ndi mankhwalawa komanso kupewa kukhudzana ndi ana.
