Mankhwalawa ali ndi mphamvu yoletsa kwambiri mabakiteriya ambiri a gram-positive ndi negative. Mabakiteriya tcheru mankhwala sulfonamide sangagwiritse ntchito kupatsidwa folic acid m'madera ozungulira, akhoza ntchito p-aminobenzoic asidi ndi dihydropteridine, pansi pa zochita za bakiteriya dihydrofolate synthase synthesize tetrahydrofolate, adamulowetsa tetrahydrofolate mu synthesis purine, thymine nucleoside amatenga mbali yofunika kwambiri mu kusamutsa mpweya gulu. Mankhwala a sulfa ndi ofanana mu dongosolo la p-aminobenzoic acid, ndipo amatha kupikisana ndi p-aminobenzoic acid kwa dihydrofolate synthetase mu mabakiteriya, kulepheretsa kaphatikizidwe ka dihydrofolate, pamapeto pake zimakhudza kaphatikizidwe ka nucleic acid, ndikulepheretsa kukula ndi kubereka kwa mabakiteriya. Zochita za mankhwala a sulfanilamide zimatha kutsutsidwa ndi mankhwala omwe amatha kusokoneza amino benzoic acid, monga procaine ndi tetracaine. Kuphatikiza apo, mafinya ndi kuwonongeka kwa minofu kumaperekanso zinthu zofunika pakukula kwa bakiteriya, komanso kukhala ndi zotsatira zotsutsana ndi sulfonamides. Trimethoprim ndi antibacterial synergist yomwe imalepheretsa ntchito ya dihydrofolate reductase. Kuphatikiza awiriwa kungapangitse synergistic zotsatira kumapangitsanso antibacterial kwenikweni.
Sulfonamides antibacterial mankhwala, ambiri mabakiteriya gram zabwino ndi zoipa mabakiteriya ndi amphamvu chopinga tingati, ntchito ziweto ndi nkhuku escherichia coli ndi pasteurella matenda. Angagwiritsidwenso ntchito pa nkhumba toxoplasmosis, nkhuku ndi kalulu coccidiosis.
Ndi mankhwala. Kwa mkati makonzedwe: tsiku mlingo, pa 1kg thupi, 32mg nkhumba ndi nkhuku; kwa nkhumba, kwa masiku 5 mpaka 10; ndi nkhuku, kwa masiku 3 mpaka 6. Kudyetsa kosakaniza: Izi 100g kusakaniza 500 ~ 750kg, kugwiritsa ntchito nkhumba mosalekeza 5 ~ 10 masiku, kugwiritsa ntchito nkhuku mosalekeza 3 ~ 6 masiku. Chakumwa chosakaniza: 100g ya mankhwalawa wothira madzi 1000- 1500kg, omwe amagwiritsidwa ntchito masiku 5-10 a nkhumba, 3 ~ 6 masiku a nkhuku.
